Section: Module 9: Lesson 5: Eukaryotic Gene Regulation | Biochemistry | NextGenU.org
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Student Learning Outcomes:
Upon completion of this lesson, you will be able to:
- Define differential gene expression.
- Distinguish between heterochromatin and euchromatin.
- Explain how DNA methylation and histone acetylation affects chromatin structure and the regulation of transcription.
- Define epigenetic inheritance.
- Describe the role of the transcription initiation complex.
- Define control elements and explain how they influence transcription.
- Distinguish between general and specific transcription factors.
- Explain the role of promoters, enhancers, activators, and repressors in transcriptional control.
- Explain how eukaryotic genes can be coordinately expressed.
- Describe the process and significance of alternative RNA splicing.
- Describe the processing of pre-mRNA in eukaryotes.
- Describe factors that influence the lifespan of mRNA in the cytoplasm.
- Explain how gene expression may be controlled at the translational and posttranslational level.
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Students mustMark as done
Required Learning Resources and Activities
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Students mustView
Read the section under eukaryotic gene regulation. (25 minutes)
Western Oregon University - N. D
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Students mustViewStart discussions: 1
General Instructions
In this activity, you will describe transcription factors and the preinitiation complex (PIC), the process of translation, prokaryotic gene regulation, and eukaryotic gene regulation. To achieve this, you will review all the study materials for Module 9.
Step 1: Select and Reflect
Read “Translation” from the learning resources under RNA.
Step 2: Respond
Using supporting data to back your arguments, prepare a 500-600 word written piece which discusses the following:
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Explain, in detail, the step-by-step process of translating the language of nucleotides into the language of amino acids in prokaryotes and eukaryotes
Step 3: Share
To share your work, click on the “Add a new discussion topic” button under this post and paste your work into the “Message” box. Make sure to reference others’ intellectual property when necessary. All references should follow 7th Edition APA formatting. For further instructions, see the resource on the Himmelfarb Health Sciences Library: APA citation resource (N.B.: references are excluded from word counts).
Step 4: Interact
To complete the activity, evaluate and categorize the work from one of your peers based on items A - E of the rubric below. Provide a rationale for the grade you have provided, as well as comments or suggestions for improvement. To post a reply, click “Reply” on a particular discussion, write your feedback and then click on “Post to forum.” You can use the list below as an example:
Item A is .…. because…. My suggestions for improvement are….
Item B is .…. because…. My suggestions for improvement are….
Item C is .…. because…. My suggestions for improvement are….
Item D is .…. because…. My suggestions for improvement are….
Item E is .…. because…. My suggestions for improvement are….OPTIONAL Step 5: Interact (10 minutes)
If you would like to, you can reply to your peers' posts in a respectful and professional manner. Ensure that your post engages your peers' ideas by including a reflection on their comments, sharing ideas of other potential difficulties and parties involved, or asking thought-provoking questions. If a peer comments on your posting, please reply. To post a reply, click “Reply” on a particular discussion, write your feedback and then click on “Post to forum.”
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Quiz: Module 9
To access the quiz, click on the name of the quiz provided above. On the following screen, click the attempt quiz button to view the case studies and respond to the questions.
TO PASS THIS QUIZ YOU MUST OBTAIN A SCORE OF 80%.