General Instructions

In this activity, you will be given a series of questions. These questions will involve retrosynthetic analysis and investigating stereochemistry and chemoselectivity. The link to a chemistry drawing tool is provided; you should explore the features and familiarize yourself with the functions before starting the activity. Note that you are not required to share the structures or mechanisms you drew when sharing your responses.

Step 1 - Review

Review the material from this module, paying particular attention to retrosynthetic analysis, chemoselectivity, and stereoselectivity.

Answer the following questions:

1. Explain the method/steps you would use to plan a multi-step synthesis. Are any steps more important than others? Why?
   

2. Explain the importance of considering chemoselectivity and stereoselectivity when planning a synthesis and provide an example of a reaction that highlights the importance of these considerations.
   

3. Design a synthetic route for the following product and explain the mechanism involved:
   
   You can practice drawing the mechanism in the chemistry tool.

Step 3: Share 

To share your work, click the “Add a new discussion topic” button under this post and paste your work into the “Message” box. Make sure to reference others’ intellectual property when necessary. All references should follow 7th Edition APA formatting. For further instructions, see the resource on the Himmelfarb Health Sciences Library: APA citation resource (N.B.: references are excluded from word counts). Note that you do not need to share your drawings done in the Chemistry tool, but you can discuss them if needed.

Step 4: Interact