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Organic Chemistry 1
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Principles of Organic Synthesis
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Module 1: Lesson 1: Functional Groups and Families
Functional Groups Names, Properties, and Reactions
Functional Groups
Module 1: Lesson 2: Alkanes
Nomenclature
Reactions of Alkanes
Alkane Conformational Analysis
Module 1: Lesson 3: Cycloalkanes
Cycloalkanes
Cycloalkanes and their Relative Stabilities
Conformation Analysis of Cyclohexane
Substituted Cyclohexanes
Learning Activity 1 - Organic Compounds - Nomenclature and Functional Groups (2 hours)
Module 2: Stereochemistry
Module 2: Lesson 1: Geometric Isomers and the E/Z Naming System
Geometric Isomers and E/Z Naming System
Module 2: Lesson 2: Enantiomers
Chirality and R/S Naming System
Module 2: Lesson 3: Optical Activity
Optical Activity
Module 2: Lesson 4: Fisher Projection
Fisher Projection
Module 2: Lesson 5: Compounds with More Than One Chirality Centers
Compounds with More Than One Chirality Centers
Learning Activity 2 - Stereochemistry (2 hours)
Module 3: Structure and Bonding
Module 3: Lesson 1: Review of Structure and Bonding
Quantum Numbers for Atoms
Molecular Orbital Theory
Double and Triple Bonds
Resonance
Module 3: Lesson 2: Chemical Bonding Theory
Bonding & Molecular Structure
Module 3: Lesson 3: Chemical Bonds
Drawing Organic Structures
Module 3: Lesson 4: Resonance
Resonance
Module 3: Lesson 5: Review of Molecular Orbital Theory
Molecular Orbital Theory
Molecular Orbital Theory- Conjugation and Aromaticity
Module 3: Lesson 6: Hybridization
Hybridization
Module 3: Lesson 7: Acidity of Organic Molecules
Lewis Acids and Lewis Bases
All Other Things Being Equal Electron Withdrawing Groups Tend to Make Lewis Acids Stronger and Bases Weaker While Electron Donating Groups Tend to Make Lewis Bases Stronger and Acids Weaker
Module 3: Lesson 8: Bond Length and Strength
Bond Lengths, Bond Strengths, and Bond Angles
Learning Activity 3 - Structure and Bonding (2 hours)
Module 4: Free Radical Reactions
Module 4: Lesson 1: Free Radicals
Organic Radicals
Module 4: Lesson 2: Free Radical Substitution Reaction of Alkanes
Homolytic and Heterolytic Cleavage
Halogenation Reaction of Alkanes
Module 4: Lesson 3: Stability of Alkyl Radicals
Stability of Alkyl Radicals
Module 4: Lesson 4: Stereochemistry for Halogenation of Alkanes
Chlorination vs. Bromination
Stereochemistry for Halogenation of Alkanes
Learning Activity 4 - Free Radical Reactions (2 hours)
Module 5: Mechanisms of Substitution and Elimination Pathways
Module 5: Lesson 1: Nucleophilic Substitution Reaction Overview
Nucleophilic Substitution Reaction Overview
Module 5: Lesson 2: SN2 Reaction Mechanism, Energy Diagram, and Stereochemistry
SN2 Reaction Mechanism, Energy Diagram, and Stereochemistry
Other Factors that Affect SN2 Reactions
Module 5: Lesson 3: SN1 Reaction Mechanism, Energy Diagram, and Stereochemistry
SN1 Reaction Mechanism, Energy Diagram, and Stereochemistry
Module 5: Lesson 4: SN1 vs. SN2
SN1 vs. SN2
Module 5: Lesson 5: Extra Topics on Nucleophilic Substitution Reaction
Extra Topics on Nucleophilic Substitution Reaction
Module 5: Lesson 6: Elimination Reactions
Elimination Reactions
E2 Reactions
E1 Reactions
Module 5: Lesson 7: Reaction Rates of Substitution and Elimination Reactions
Comparison and Competition Between SN1, SN2, E1, and E2
Learning Activity 5 - Mechanisms of Substitution and Elimination Pathways (2 hours)
Module 6: Alkenes
Module 6: Lesson 1: Nomenclature, Structure, and Synthesis of Alkenes
Organic Nomenclature
Module 6: Lesson 2: Synthesis of Alkenes
Synthesis of Alkenes
Module 6: Lesson 3: Reactivity of Alkenes
Addition of Hydrogen Halide to Alkenes
Addition of Water (or Alcohol) to Alkenes
Addition of Bromine and Chlorine to Alkenes
Hydrogenation
Two Other Hydration Reactions of Alkenes
Oxidation Reactions of Alkenes
Learning Activity 6 - Alkenes (2 hours)
Module 7: Lesson 1: Nomenclature, Reactivity, and Synthesis of Alkynes
Organic Nomenclature
Alkyne Reactivity
Learning Activity 7 - Alkynes (2 hours)
Module 8: Lesson 1: Structure, Bonding, Nomenclature, and Acidity of Alcohols
Naming Alcohols and Phenols
Properties of Alcohols and Phenols
Module 8: Lesson 2: Synthesis of Alcohols
Preparation of Alcohols - A Review
Alcohols from Carbonyl Compounds - Reduction
Alcohols from Carbonyl Compounds - Grignard Reagents
Module 8: Lesson 3: Reaction of Alcohols
Reactions of Alcohols
Module 8: Lesson 4: Reaction of Alcohols
Oxidation of Alcohols
Module 8: Lesson 5: Selective Oxidation Reactions
Selective Oxidation Reactions
Ether Protective Groups
Learning Activity 8 - Alcohol - Structure, Synthesis, Reactivity (2 hours)
Module 9: Lesson 1: Synthetic Strategy, Methods, and Analysis in Organic Chemistry
Principles of Organic Synthesis
Organic Synthesis
Module 9: Lesson 2: Retrosynthetic Analysis
Synthesis of Target Molecules: Introduction to Retrosynthetic Analysis
An introduction to Retrosynthetic Analysis
Learning Activity 9 - Introduction to Synthetic Strategy (2 hours)
Final Exam
Course and Self Evaluation & Certificate
Course Activities
Learning Activities.
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Module 9: Lesson 1: Synthetic Strategy, Methods, and Analysis in Organic Chemistry
Principles of Organic Synthesis
Principles of Organic Synthesis
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Course Registration
Peer Corner
Pre-Test
Announcements
Functional Groups Names, Properties, and Reactions
Functional Groups
Nomenclature
Reactions of Alkanes
Alkane Conformational Analysis
Cycloalkanes
Cycloalkanes and their Relative Stabilities
Conformation Analysis of Cyclohexane
Substituted Cyclohexanes
Learning Activity 1 - Organic Compounds - Nomenclature and Functional Groups (2 hours)
Geometric Isomers and E/Z Naming System
Chirality and R/S Naming System
Optical Activity
Fisher Projection
Compounds with More Than One Chirality Centers
Learning Activity 2 - Stereochemistry (2 hours)
Quantum Numbers for Atoms
Molecular Orbital Theory
Double and Triple Bonds
Resonance
Bonding & Molecular Structure
Drawing Organic Structures
Resonance
Molecular Orbital Theory
Molecular Orbital Theory- Conjugation and Aromaticity
Hybridization
Lewis Acids and Lewis Bases
All Other Things Being Equal Electron Withdrawing Groups Tend to Make Lewis Acids Stronger and Bases Weaker While Electron Donating Groups Tend to Make Lewis Bases Stronger and Acids Weaker
Bond Lengths, Bond Strengths, and Bond Angles
Learning Activity 3 - Structure and Bonding (2 hours)
Organic Radicals
Homolytic and Heterolytic Cleavage
Halogenation Reaction of Alkanes
Stability of Alkyl Radicals
Chlorination vs. Bromination
Stereochemistry for Halogenation of Alkanes
Learning Activity 4 - Free Radical Reactions (2 hours)
Nucleophilic Substitution Reaction Overview
SN2 Reaction Mechanism, Energy Diagram, and Stereochemistry
Other Factors that Affect SN2 Reactions
SN1 Reaction Mechanism, Energy Diagram, and Stereochemistry
SN1 vs. SN2
Extra Topics on Nucleophilic Substitution Reaction
Elimination Reactions
E2 Reactions
E1 Reactions
Comparison and Competition Between SN1, SN2, E1, and E2
Learning Activity 5 - Mechanisms of Substitution and Elimination Pathways (2 hours)
Organic Nomenclature
Synthesis of Alkenes
Addition of Hydrogen Halide to Alkenes
Addition of Water (or Alcohol) to Alkenes
Addition of Bromine and Chlorine to Alkenes
Hydrogenation
Two Other Hydration Reactions of Alkenes
Oxidation Reactions of Alkenes
Learning Activity 6 - Alkenes (2 hours)
Organic Nomenclature
Alkyne Reactivity
Learning Activity 7 - Alkynes (2 hours)
Naming Alcohols and Phenols
Properties of Alcohols and Phenols
Preparation of Alcohols - A Review
Alcohols from Carbonyl Compounds - Reduction
Alcohols from Carbonyl Compounds - Grignard Reagents
Reactions of Alcohols
Oxidation of Alcohols
Selective Oxidation Reactions
Ether Protective Groups
Learning Activity 8 - Alcohol - Structure, Synthesis, Reactivity (2 hours)
Organic Synthesis
Synthesis of Target Molecules: Introduction to Retrosynthetic Analysis
An introduction to Retrosynthetic Analysis
Learning Activity 9 - Introduction to Synthetic Strategy (2 hours)
Learning Activities.
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