Section: Module 6: Lesson 1: Principles of Cancer Genetics | Breast Health

Section: Module 6: Lesson 1: Principles of Cancer Genetics | Breast Health | NextGenU.org

Student Learning Outcomes:

Upon completion of this lesson, you will be able to:

Differentiate between dominant and recessive inheritance.

Explain variable penetrance in BRCA mutations.

Recognize clinical features of hereditary breast cancer syndromes, including PALB2, ATM, and CHEK2.

Click here to start this lesson
- Select activity Required Learning Resources
  
  Required Learning Resources
- Select activity Your Guide to Understanding Genetic Conditions: Breast Cancer
  
  Your Guide to Understanding Genetic Conditions: Breast Cancer URL
  
  Students must
  
  Mark as done
  
  Read the sections titled "Description", "Frequency", "Causes", and "Inheritance Pattern". This resource provides information about hereditary breast cancer. (9 minutes)
  National Institutes of Health, U.S. National Library of Medicine - 2015
- Select activity Reduced penetrance BRCA1 and BRCA2 pathogenic variants in clinical germline genetic testing
  
  Reduced penetrance BRCA1 and BRCA2 pathogenic variants in clinical germline genetic testing URL
  
  Students must
  
  Mark as done
  
  Read the entire article. (20 minutes)
  npj Precision Oncology volume - 2024
- Select activity Supplementary Learning Resources (Not Required) (copy)
  
  Students must
  
  Mark as done
  
  Supplementary Learning Resources (Not Required)
- Select activity Genetics of breast cancer: a topic in evolution
  
  Genetics of breast cancer: a topic in evolution URL
  
  Students must
  
  Mark as done
  
  Read the article to learn more about the genetics of breast cancer. (31 min)
  S. Shiovitz and L. A. Korde - 2015

Introduction

Course Registration

Pre-Test

Peer Corner

Module 1: Anatomy of the Breast

Lesson Summary: Module 1: Module 1: Anatomy of the Breast

Study Guide: Module 1: Anatomy of the Breast

Flashcards Module 1: Anatomy of the Breast

Microlearning Module 1: Anatomy of the Breast

Module 1: Lesson 1: Gross Anatomy of the Breast

Overview of the Breast - Anatomy &amp; Physiology of the Breast

Breast Anatomy

Lymphatic drainage of the breast

The Lymphatic System in Breast Cancer: Anatomical and Molecular Approaches

Module 1: Lesson 2: Histologic Anatomy of the Breast

Anatomy Atlases - Atlas of Microscopic Anatomy - A Functional Approach: Companion to Histology and Neuroanatomy: Second Edition

Simplified diagram of the anatomy of the breast

TDLU; terminal duct lobular unit; TDLUs

Discussion Forum: Anatomy of the Breast

Module 2: Physiology of the Breast

Lesson Summary: Module 2: Physiology of the Breast

Study Guide: Module 2: Physiology of the Breast

Flashcards Module 2: Physiology of the Breast

Microlearning Module 2: Physiology of the Breast

Module 2: Lesson 1: Breast Development

Molecular Mechanisms Guiding Embryonic Mammary Gland Development

Hormones and Breast Development: A Deep Dive

Changes in the mammary gland during aging and its links with breast diseases

Module 2: Lesson 2: Reproductive Cycle Changes

Physiological changes in the mammary glands during a female’s life

Physiology of Lactation

Breastfeeding Care Plan Chart

Discussion Forum: Physiology of the Breast

Module 3: Benign Disorders of the Breast

Lesson Summary: Module 3: Benign Disorders of the Breast

Study Guide: Module 3: Benign Disorders of the Breast

Flashcards Module 3: Benign Disorders of the Breast

Microlearning Module 3: Benign Disorders of the Breast

Module 3: Lesson 1: Nipple Discharge and Galactorrhea

Nipple Discharge

Galactorrhea

Nipple Discharge

Nipple Discharge: An Early Warning Sign of Breast Cancer

Nipple Discharge: Current Clinical and Imaging Evaluation

DBT-galactography: a promising tool for improving the diagnostic workup of nipple discharge

Module 3: Lesson 2: Breast Pain and Infections

Is Your Breast Pain Cyclical or Non-Cyclical? How to Tell

Inflammatory diseases of the non-lactating female breasts

Non-Lactational Mastitis: Symptoms, Diagnosis, and Care

Academy of Breastfeeding Medicine Clinical Protocol #36: The Mastitis Spectrum, Revised 2022

Mastalgia (Breast Pain)

Antibiotics and Mastitis: New ABM Protocol

Module 3: Lesson 3: Breast Masses and Structural Abnormalities

Fibroadenoma Vs Cyst: Understanding The Difference

A Comprehensive Review of Breast Fibroadenoma: Correlating Clinical and Pathological Findings

Optimal strategies for addressing developmental breast asymmetry and the significance of symmetrical treatment: A systematic review

Introduction Breast Exam

Breast Examination Techniques

Discussion Forum: Benign Disorders of the Breast

Module 4: Routine Screening for Selected Diseases of the Breast

Lesson Summary: Module 4: Routine Screening for Selected Diseases of the Breast

Study Guide: Module 4: Routine Screening for Selected Diseases of the Breast

Flashcards Module 4: Routine Screening for Selected Diseases of the Breast

Microlearning Module 4: Routine Screening for Selected Diseases of the Breast

Module 4: Lesson 1: Breast Cancer Screening Principles

Mammograms, Ultrasounds and MRIs: What's the Difference?

New Recommendations for Breast Cancer Screening—In Pursuit of Health Equity

Limitations of Mammograms

Module 4: Lesson 2: Management of Benign Breast Findings

Approach to the Breast Mass

Current Management and Treatment Options for Breast Pain

Prolactinoma

Hyperprolactinemia with Galactorrhea Due to Subclinical Hypothyroidism: A Case Report and Review of Literature

Discussion Forum: Routine Screening for Selected Diseases of the Breast

Module 5: Epidemiology and Risk Assessment for Breast Cancer

Lesson Summary: Module 5: Epidemiology and Risk Assessment for Breast Cancer

Study Guide: Module 5: Epidemiology and Risk Assessment for Breast Cancer

Flashcards Module 5: Epidemiology and Risk Assessment for Breast Cancer

Microlearning Module 5: Epidemiology and Risk Assessment for Breast Cancer

Module 5: Lesson 1: Breast Cancer Risk Factors

Overview of the Breast - Anatomy & Physiology of the Breast