Section: Module 1: Lesson 3: Carboxylic Acid Derivatives | Organic Chemistry 2 | NextGenU.org
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Upon completion of this module, students you will be able to:Student Learning Outcomes:
- Apply the IUPAC rules for naming carboxylic acid derivatives, including the nomenclature for the cyclic version of the molecule.
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Identify the reactant types used in acyl substitution reactions to form the major carboxylic acid derivatives, such as amides and esters.
- Describe the mechanism of nucleophilic acyl substitution reactions.
- Identify the conditions that would lead to spontaneous decarboxylation of a carboxylic acid.
- Predict the products of an acyl substitution reaction.
- Order carboxylic acid derivatives (anhydrides, esters, and amides) based on their reactivity.
- Explain how strong acid and strong base conditions would impact the mechanism of hydrolysis of an amide.
- Identify the nucleophile and electrophile within nucleophilic acyl substitution reactions.
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Students mustMark as done
Required Learning Resources and Activities
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Students mustView
Read the sections on Derivatives of Carboxylic Acids. (31 minutes)
Virtual Textbook of Organic Chemistry Michigan State - 2013
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Students mustView
Read the sections on Amine reactivity. (20 minutes)
Virtual Textbook of Organic Chemistry Michigan State - 2013
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Students mustView
Read the sections on Reactions of Amines. (15 minutes)
Virtual Textbook of Organic Chemistry Michigan State - 2013
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Students mustView
Read the sections on The Leuckart Reaction and Pyrolytic syn-Elimination. (5 minutes)
Virtual Textbook of Organic Chemistry Michigan State - 2013