Section: Module 2: Lesson 3: Reactivity of Aldehydes and Ketones | Organic Chemistry 2 | NextGenU.org

  • Student Learning Outcomes:
    Upon completion of this module, students you will be able to:
    • Explain the formation of stable hydrates and hemiacetals from adding water to aldehydes and ketones.
    • .Explain the reaction mechanisms and distinguish the formation of acetals by the reaction of aldehydes and ketones with two equivalents of alcohol and the elimination of water.
    • Explain the formation of imine derivatives from the reaction of aldehydes and ketones with ammonia or 1º-amines (Schiff bases).
    • Break down the formation of enamine and cyanohydrin from the reaction of aldehydes and ketones with 2º-amines and hydrogen cyanide, respectively.
    • Deduce the products formed by the reduction of aldehydes and ketones by complex metal hydrides and by adding organometallic reagents.
    • Break down the reaction products and mechanisms for the reduction of aldehydes and ketones.
    • Outline the oxidation of aldehydes to carboxylic acids using oxidizing agents.
    Approximate time required for the readings for this lesson (at 144 words/minute): 6 hours and 41 minutes.

    Click here to start this lesson

    • Required Learning Resources and Activities
    • Read the entire page. (20 minutes)

      Chemistry LibreText - 2020

    • Read the entire page. (20 minutes)

      Chemistry LibreText - 2023

    • Read the entire page. (25 minutes)

      Chemistry LibreText - 2019

    • Read the entire page. (15 minutes)

      Chemistry LibreText - 2019

    • Read the entire page. (20 minutes)

      Chemistry LibreText - 2023

    • Read the entire page. (10 minutes)

      Chemistry LibreText - 2022

    • General Instructions:

      In this activity, you will demonstrate your understanding of the synthesis of carboxylic acids, their derivatives, and their various reactions.

      Step 1: Select and Reflect

      Select one of the topics below and demonstrate your understanding of them in theoretical and practical settings:

      • Synthesis of Aldehydes and Ketones

      • Reactivity of Aldehydes and Ketones

      Step 2: Respond

      Answer any one of the following questions: 

      1. What is the name of the reaction in the diagram below? Explain the role of the catalysts and show (with chemical structures) the three steps involved, from the reactants to the formation of the final products.


      1. With the aid of appropriate chemical reactions, show how the addition of water affects the formation of stable hydrates and hemiacetals from aldehydes and ketones.

      2. a. Name the natural sources of the following aldehydes and ketones:


      b. Name the following reactions, draw the structures of the products, and name the structures (you can use the chemistry tool to draw out any structures or mechanisms to help you answer).



      Step 3: Share 

      To share your work, click on the “Add a new discussion topic” button under this post and paste your work into the “Message” box. Make sure to reference others’ intellectual property when necessary. You do not need to share your drawings that were done in the chemistry tool, but you can discuss them if needed. All references should follow 7th Edition APA formatting. For further instructions, see the resource on the Himmelfarb Health Sciences Library: APA citation resource (N.B.: references are excluded from word counts).

      Step 4: Interact 

      To complete the activity, evaluate and categorize the work from one of your peers based on items A - E of the rubric below. Provide a rationale for the grade you have provided and comments or suggestions for improvement. To post a reply, click “Reply” on a particular discussion, write your feedback, and click “Post to forum.” You can use the list below as an example:

      Item A is….. because ….. My suggestions for improvement are …..

      Item B is ….. because ….. My suggestions for improvement are…..

      Item C is ….. because ….. My suggestions for improvement are…..

      Item D is ….. because …… My suggestions for improvement are ……

      Item E is ….. because ….. My suggestions for improvement are …..

      OPTIONAL Step 5: Interact (10 minutes)

      If you would like to, you can reply to your peers' posts in a respectful and professional manner. Ensure that your post engages your peers' ideas by including a reflection on their comments, sharing ideas of other potential difficulties and parties involved, or asking thought-provoking questions. If a peer comments on your posting, please reply. To post a reply, click “Reply” on a particular discussion, write your feedback and then click on “Post to forum.”



    • quiz icon
      Quiz: Module 2

      To access the quiz, click on the name of the quiz provided above. On the following screen, click the "Preview quiz now" button to respond to the questions.

      TO PASS THIS QUIZ YOU MUST OBTAIN A SCORE OF 80%.

      Not available unless: The activity Quiz: Module 1 is marked complete