Student Learning Outcomes:

• Describe the relationship between steric hindrance and reactivity.
• Define tautomerization and draw basic and acidic tautomerizations.
  
• Identify the thermodynamically favored tautomer of an aldehyde or ketone.
  
• Predict the role of an enolate carbanion in a reaction.
  
• Describe the conditions that favor keto and enol forms.
  
• Describe alpha carbon reaction mechanisms incorporating enols for neutral/ acidic reactions and enolates for basic reactions.
  
• Determine if a kinetic or thermodynamic enolate will form based on reaction conditions.
  
• Describe kinetic and thermodynamic enolate reaction mechanisms.
  
• Describe mechanisms for halogenation at alpha carbon and direct enolate alkylation.
  

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