Section: Module 3: Lesson 1: Multifactorial Cardiovascular Risk Profiles | Adult Cardiovascular Disease Prevention | NextGenU.org

  • Student Learning Outcomes:
    Upon completion of this lesson, you will be able to:
    • Explain the importance and use of risk estimation.
    • Describe various successful risk estimation tools in CVD prevention.
    • Define precision medicine and deep phenotyping.
    • Explain the relationship between precision medicine, deep phenotyping, and clinical decision-making.
    • Explain how success is measured in prevention programs.
    • Describe factors that determine program success.
    • Describe successful CVD prevention programs across various settings.
    • Relate the social determinants of health to CV health.

    Approximate time required for the readings for this lesson (at 144 words/minute): 10 hours and 36minutes.

    Click here to start this lesson

    • Required Learning Resources and Activities
    • Read the entire article. (25 minutes)

      2020

    • Read the entire article. (35 minutes)

      European Heart Journal. - 2020

    • Read the content under the following headings: (33 minutes)
      - Abstract
      - Genetic Basis of Inherited Cardiovascular Disease
      - Modes of Genetic Inheritance
      - Types of Genetic Variations
      - Approach to Cardiac Genetic Testing
      - Analysis and Interpretation of Genetic Data
      - Role of Functional Genomics in V

      Journal of the American College of Cardiology2021

    • Read under headlines: (10 minutes)
      - What is a Phenotype?
      - Why “Deep” Phenotyping?
       

      NIH 2012

    • Read the content under the following headings: (16 minutes)
      - Clinical Utility of Cardiac Genetic Testing
      - Recent Developments in the Field
      - Ethical, Legal, and Societal Implications
      - Conclusions

      Journal of the American College of Cardiology 2021

    • Read the entire page. (28 minutes)

      NIH 2014

    • Read the entire article. (31 minutes)

      2019

    • Read the following sections: (35 minutes)
      -Evidence–Practice Gaps in the Prevention and Management of CVD
      -Barriers to Evidence-Based and Efficient CVD Management
      -Targets for Resource-Effective Strategies
      -Resource-Effective Strategies to Prevent and Manage CVD.

    • Read the entire article. (35 minutes)

      2022

    • Read the entire article. (40 minutes)

      2021

    • General Instructions: In this activity, you will review and recall criteria and concepts about cardiac risks and their estimation, distinguish between vital concepts such as precision medicine, deep phenotyping, and clinical decision-making, and recognize the components that make a prevention program successful.

      Review the four essential points of the case and answer the fifth question based on the clinical case.

      Step 1 - Review: Consider the following scenario:

      Clinical Case: A 45-year-old female patient presents to the clinic for a routine check-up. She has no current complaints but has a family history of heart disease. The physician, Dr. McRife, decides to assess her cardiovascular risk using various risk estimation tools.

      Dr. McRife explains to the patient the importance of estimating her risk for cardiovascular disease (CVD) to implement preventative measures and reduce her chances of developing heart disease.

      Dr. McRife uses various risk estimation tools, such as the Framingham Risk Score and the American College of Cardiology/American Heart Association Pooled Cohort Equations, to assess the patient’s risk for CVD. These tools consider age, sex, blood pressure, cholesterol levels, and smoking status to estimate the patient’s 10-year risk for developing CVD.

      Dr. McRife also discusses with the patient the potential benefits of precision medicine and deep phenotyping in clinical decision-making. By using advanced technologies to gather detailed information about the patient’s genetics, lifestyle, and environment, the physician can tailor prevention and treatment strategies to the patient’s unique needs.

      Based on the results of the risk estimation tools and the patient’s characteristics, the physician recommends a CVD prevention program that includes lifestyle changes such as healthy eating, regular exercise, and smoking cessation. The physician also discusses successful CVD prevention programs that have been implemented in various settings, such as community clinics and workplace wellness programs.

      Step 2 - Respond: Answer the following questions based on Dr. McRife's actions:

      • Explain why estimating your risk for CVD is essential.
      • Describe some of the risk estimation tools used in CVD prevention.
      • Explain the relationship between precision medicine, deep phenotyping, and clinical decision-making.
      • How can advanced technologies be used to gather detailed information about a person’s genetics, lifestyle, and environment?
      • How can this information be used to tailor prevention and treatment strategies for CVD?

      Step 3 - Share: To share your work, click the "Add a new discussion topic" button under this post and paste your work into the "Message" box. Remember to reference others' intellectual property when necessary. Make sure all references follow the 7th Edition APA formatting. For further instructions, see the resource on the Himmelfarb Health Sciences Library: APA citation resource (Note: references are excluded from word counts).

      Step 4 - Interact: To complete the activity, you must reply to at least two posts made by your peers in a respectful and professional manner. Make sure your post engages with your peers' ideas by reflecting on their comments, sharing ideas about potential difficulties and parties involved, or asking thought-provoking questions. If a peer comments on your post, please reply. To post a reply, click "Reply" on a specific discussion, write your feedback, then click "Post to forum."

      OPTIONAL Step 5: Interact (10 minutes)

      If you would like to, you can reply to your peers' posts in a respectful and professional manner. Ensure that your post engages your peers' ideas by including a reflection on their comments, sharing ideas of other potential difficulties and parties involved, or asking thought-provoking questions. If a peer comments on your posting, please reply. To post a reply, click “Reply” on a particular discussion, write your feedback and then click on “Post to forum.”


    • Recommended Additional Readings

    • Read the entire article. (7 minutes)

      NIH - 2021

    • Read the entire article. (8 minutes)

      American College of Cardiology 2020

    • Read the entire article. (41 minutes)

      2020